专利名称：TREATMENT OF CANCERS发明人：BAGULEY, Bruce, Charles 36a Olsen
Avenue,ATWELL, Graham, John 192 GowingDrive,DENNY, William, Alexander 165Gossamer Drive,FINLAY, Graeme, John 58Glenvar Road,REWCASTLE, Gordon, William107 Grande Vue Road
申请号：EP93913256.0申请日：19930528公开号：EP0642343A1公开日：19950315
摘要：A new treatment schedule for administration of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and other related carboxamide anticancerdrugs in which the drug is administered in a divided-dose shedule comprising two or moreadministrations at frequent intervals, for example every hour. Schedules to produce cyclicpeaks/troughs in plasma levels are mentioned. The compounds can be used forcircumventing multidrug resistance in cancers and may, for example, be used incombination with other cytotoxic drugs, especially non-topo II inhibitors. Treatment ofmelanoma and advanced colon cancer is included.
申请人：XENOVA LIMITED
地址：240 Bath Road Slough, Berkshire SL1 4EF GB
国籍：GB
代理机构：Woods, Geoffrey Corlett
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