专利名称：CVS TRANSPLANTATION FOR TREATMENT
OF BACTERIAL VAGINOSIS
发明人：ENSIGN, Laura,CONE, Richard,HANES, Justin申请号：EP15819964.6申请日：20151210公开号：EP3233098A1公开日：20171025
摘要：Methods and materials for treating bacterial vaginosis (“BV”) are provided.Cervicovaginal secretions (“CVS”) from a woman with Lactobacillus crispatus-dominated(>50%) vaginal microbiota is transplanted to women with BV as a method for restoringbeneficial vaginal microbial communities and/or increasing resistance to sexuallytransmitted disease. Efficacy can be enhanced, or the properties of the endogenous CVSimproved, through administration of an acidifying agent such as lactic acid. The examplesdemonstrate the role of healthy CVS in disease resistance, and the effect of pH on CVSproperties. The examples also describe the collection and transplantation of healthybeneficial CVS into women at risk for, or after treatment for, BV.
申请人：The Johns Hopkins University
地址：3400 North Charles Street Baltimore, MD 21218 US
国籍：US
代理机构：Potter Clarkson LLP
更多信息请下载全文后查看
因篇幅问题不能全部显示，请点此查看更多更全内容