Prodrug acid esters of [2-(4-benzyl-3-hydroxy-pipe

专利名称：Prodrug acid esters of [2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethansulfonyl]phenol

发明人：Alexander Alanine,Bernd

Buettelmann,Holger Fischer,Marie-PauleHeitz Neidhart,Joerg Huwyler,GeorgJaeschke,Emmanuel Pinard,Rene Wyler

申请号：US09931431申请日：20010816

公开号：US20020040037A1公开日：20020404

摘要：The invention is a compound of the formulawhereinR isa) -C(O)(CH2)nC(O)OH,b)wherein R1 is -N(R2)(R3), or is a five or six member aromatic or non-aromatic heterocyclicring having one or more heteroatoms selected from nitrogen, oxygen or sulfur,unsubstituted or substituted by lower alkyl,c) -P(O)(OH)2, or isd) -C(O)(CH2)nNHC(O)(CH2)nN(R2)(R3); andR2/R3 are hydrogen or lower alkyl;n is 1, 2, 3 or 4;or apharmaceutically acceptable acid addition salt thereof

申请人：ALANINE ALEXANDER,BUETTELMANN BERND,FISCHER HOLGER,NEIDHARTMARIE-PAULE HEITZ,HUWYLER JOERG,JAESCHKE GEORG,PINARD EMMANUEL,WYLERRENE

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