专利名称:Passive desensitization发明人:Michael J. Caplan申请号:US09731221申请日:20001206
公开号:US20020018778A1公开日:20020214
摘要:IgE-blocking agents and methods of their use have been developed for
desensitizing an individual to an antigen. These IgE-blocking agents work by blocking theantigen-binding site of the IgE molecules and thereby preventing the antigen frombinding. These agents typically have up to one IgE binding site present per molecule soas prevent any cross-linking of IgE which could lead to an allergic reaction. Methods ofusing these novel IgE blocking agents include administering the agents to alleviate orprevent allergic reactions as well as administering the agents to decrease the risk ofallergic reactions during immunotherapy or “rush” immunotherapy. Compositions andkits comprising these IgE binding agents are also provided.
申请人:CAPLAN MICHAEL J.
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