Aromatic sulfonamide derivatives, their use as enz

专利名称：Aromatic sulfonamide derivatives, their use

as enzyme inhibitors and pharmaceuticalcompositions containing them

发明人：Raymond Dumont申请号：US08/785251申请日：19970117公开号：US05663174A公开日：19970902

摘要：Aromatic sulfonamide derivatives, particularly benzenesulfonamide, 4-fluorobenzenesulfonamide, 5-chloro-1- naphthalenesulfonamide and 5-isoquinolinesulfonamide derivatives are provided that inhibit Ca.sup.2+ - dependentenzymes and proteins such as Phospholipase A.sub.2, protein kinases such as ProteinKinase C, and inhibit membrane fusion, thereby being a valuable drug for the treatmentof inflammation, arthritis, infarction, nephritis and many other types of tissue injury.

申请人：PHARNO-WEDROPHARM GMBH

代理人：David L. Mossman

更多信息请下载全文后查看