专利名称:Device for Filtration of Fluids Therethrough
and Accompanying Method
发明人:Chong Wing Yung,Donald E. Ingber,Jason O.
Fiering,Mathew Varghese
申请号:US13144572申请日:20100115
公开号:US20120149021A1公开日:20120614
专利附图:
摘要:A microfluidic device for separating target components from a source fluidincludes one or more source channels connected to one or more collection channels by
one or more transfer channels. The target components of the source fluid can bemagnetic or bound to magnetic particles using a know binding agent. A source fluidcontaining magnetically bound target components can be pumped through the sourcechannel of the microfluidic device. A magnetic field gradient can be applied to the sourcefluid in the source channel causing the magnetically bound target components tomigrate through the transfer channel into the collection channel. The collection channelcan include a collection fluid that is stagnant until a predefined volume of source fluid isprocessed or a predefined volume of target components accumulate in the collectionchannel, at which point collection fluid can be pumped into the collection channel to flushthe target components out of the collection channel. The target components can besubsequently analyzed for detection and diagnosis.
申请人:Chong Wing Yung,Donald E. Ingber,Jason O. Fiering,Mathew Varghese
地址:San Jose CA US,Boston MA US,Boston MA US,Sunnyvale CA US
国籍:US,US,US,US
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