专利名称：T-cell membrane protein
发明人：Sherman M. Weissman,Miguel A. Alonso申请号：US07/031316申请日：19870326公开号：US04835255A公开日：19890530
摘要：A 16.7 kilodalton membrane protein which is produced in mature, but no early-stage, T cells has been discovered. The protein has four distinct amphipathic domains,each having an amino acid composition which is predictive of an alpha helical structurethat would be stable in a lipid bilayer. Each of these regions is flanked by a relativelypolar domain whose amino acid sequence is predictive of &bgr; pleat peptide regions. Anantibody specific against one of the polar domains can be used to discriminate mature T-cells in a mixed-cell sample.
申请人：YALE UNIVERSITY
代理人：Peter J. Dehlinger
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